| 邱进,陈向锋.供精人工授精的临床应用与子代出生安全[J].济宁医学院学报,2021,44(1):63-66 |
| 供精人工授精的临床应用与子代出生安全 |
| Clinical application of artificial insemination by donor sperm and the safety of the offspring |
| 投稿时间：2021-01-13 |
| DOI：10.3969/j.issn.1000-9760.2021.01.015 |
| 中文关键词: 不育;供精人工授精;临床应用;子代出生安全 |
| 英文关键词: Infertility;Artificial insemination by donor sperm;Clinical application;Birth safety of offspring |
| 基金项目:上海市妇女健康服务能力建设专项规划项目（FNZX0901）；山东省生殖医学重点实验室开放课题（SDKL2017018-06） |
| 作者 | 单位 | E-mail | | 邱进 | 上海交通大学医学院附属仁济医院
上海市人类精子库
上海市辅助生殖与优生重点实验室, 上海 200135 | | | 陈向锋 | 上海交通大学医学院附属仁济医院
上海市人类精子库
上海市辅助生殖与优生重点实验室, 上海 200135 | allanbacon@163.com |
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| 中文摘要: |
| 供精人工授精（artificial insemination by donorsperm，AID）技术已经得到广泛应用，不仅解决了部分男性患者的不育问题，更为他们的家庭和谐带来了益处。影响AID成功的因素主要包括女性的年龄、授精次数、促排卵方案和冷冻精子复苏前后的质量等。其中女性的年龄对AID治疗成功率的影响尤为重要。虽然AID技术对子代出生安全尚有不确定性，不过目前多数研究数据表明供精人工授精技术安全可靠。本文就该技术的临床应用和出生子代缺陷两个方面进行综述。 |
| 英文摘要: |
| Artificial insemination by donor sperm has been widely used,which not only solves the infertility problem of some male patients,but also brings benefits to their family harmony.In this paper,the clinical application of this technique and the safety of the offspring were reviewed.There are many factors affecting the success of AID,including the age of the infertile women;the times of inseminations;ovulation induction regimens and the quality of sperm before and after thawed.The age of women are particularly important for the success of AID treatment.Although there is uncertainty about the safety of the offspring,most of the current research data show that the AID treatment is safe and reliable. |
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