文章摘要
胡良晨,王艳玲,郝延磊.动脉粥样硬化性类烟雾病危险因素分析[J].济宁医学院学报,2018,41(3):185-187
动脉粥样硬化性类烟雾病危险因素分析
Analysis of risk factors for atherosclerotic moyamoya disease
投稿时间:2018-02-10  
DOI:10.3969/j.issn.1000-9760.2018.03.008
中文关键词: 动脉粥样硬化性类烟雾病;同型半胱氨酸;甘油三酯
英文关键词: Atherosclerotic moyamoya disease;Homocysteine;Triglycerides
基金项目:
作者单位E-mail
胡良晨 济宁医学院, 济宁 272067  
王艳玲 济宁医学院附属医院, 济宁 272000  
郝延磊 济宁医学院附属医院, 济宁 272000 yhao@mail.jnmc.edu.cn 
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中文摘要:
      目的 探究动脉粥样硬化性类烟雾病的危险因素。方法 回顾性分析2016年1月1日至2018年1月5日在我院住院治疗的动脉粥样硬化性类烟雾病患者56例,作为类烟雾病组,选择同期在我院进行查体的健康人40例作为对照组,对其危险因素进行logistic回归分析。结果 单因素分析发现两组间的同型半胱氨酸、甘油三酯、高密度脂蛋白、低密度脂蛋白、总胆固醇、糖化血红蛋白差异具有统计学意义(P<0.05);逐步多元logistic回归分析发现同型半胱氨酸(OR=1.489,95%CI:1.118~1.981,P=0.006)、甘油三酯(OR=8.048,95%CI:2.167~29.892,P=0.002)为动脉粥样硬化性类烟雾病的独立危险因素。结论 同型半胱氨酸、甘油三酯是动脉粥样硬化性类烟雾病的独立危险因素。
英文摘要:
      Objective To explore risk factors of atherosclerotic moyamoya disease.Methods A retrospective analysis was conducted in patients with atherosclerotic moyamoya disease who were hospitalized in our hospital between January 1,2016 and January 5,2018.In the meanwhile,the healthy population who underwent the physical examination in our hospital during the same period of time were collected as control group.The risk factors were analyzed by logistic regression analysis.Results Single factor analysis showed that triglycerides,high-density lipoprotein,low-density lipoprotein,total cholesterol,glycosylated hemoglobin and homocysteine levels were statistically significant between the two groups(P<0.05).Logistic regression analysis showed that homocysteine (OR=1.489,95%CI:1.118~1.981,P=0.006) and triglycerides (OR=8.048,95%CI:2.167~29.892,P=0.002) were independent risk factors of atherosclerotic moyamoya disease.High density lipoprotein,low density lipoprotein,total cholesterol and glycosylated hemoglobin are no longer independent risk factors.Conclusion Homocysteine and triglycerides were independent risk factors of atherosclerotic moyamoya disease.
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