| 李港,张浩,韩光魁,李根华,冯嵩,靳峰.颞浅动脉-大脑中动脉吻合术治疗成人烟雾病随访观察[J].济宁医学院学报,2017,40(1):36-40 |
| 颞浅动脉-大脑中动脉吻合术治疗成人烟雾病随访观察 |
| The follow-up observation of the clinical effects of superficial temporal artery-middle cerebral artery anastomosis on adults with moyamoya disease |
| 投稿时间：2016-12-20 |
| DOI：10.3969/j.issn.1000-9760.2017.01.009 |
| 中文关键词: 烟雾病;颞浅动脉-大脑中动脉吻合术 |
| 英文关键词: Moyamoya disease;Superficial temporal artery-middle cerebral artery anastomosis |
| 基金项目:山东省医药卫生科技发展计划项目（2014WS0518） |
| 作者 | 单位 | E-mail | | 李港 | 济宁医学院, 济宁 272067 | | | 张浩 | 济宁医学院附属医院, 济宁 272029 | | | 韩光魁 | 济宁医学院附属医院, 济宁 272029 | | | 李根华 | 济宁医学院附属医院, 济宁 272029 | | | 冯嵩 | 济宁医学院附属医院, 济宁 272029 | | | 靳峰 | 济宁医学院附属医院, 济宁 272029 | jinfengsdjn@163.com |
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| 中文摘要: |
| 目的 探讨颞浅动脉-大脑中动脉吻合术（STA-MCA吻合术）治疗成人烟雾病的临床疗效。方法 收集2013年01月至2016年01月在济宁医学院附属医院诊断为烟雾病并行STA-MCA吻合术治疗的成人患者71例，通过电话、门诊或住院复查进行随访观察，并根据患者术前、后改良Rankin评分（modified Rankin Scale score，mRS评分）、颅脑灌注CT等评价STA-MCA吻合术的疗效，数据采用SPSS20.0进行分析。结果 71例成人烟雾病患者平均随访时程（27.3±8.6）月，无失访患者。61例（85.9%）患者原有临床症状得到改善，术后6月mRS评分及颅脑洪流CT结果较术前改善，差异有统计学意义（P< 0.05）。术后并发症9例，随访末期发生脑血管事件11例。结论 STA-MCA吻合术能够增加烟雾病患者的脑部血供，改善患者的临床症状，是治疗成人烟雾病的有效方法。 |
| 英文摘要: |
| Objective To analyze the efficacy of superficial temporal artery-middle cerebral artery anastomosis (STA-MCA) on adults with moyamoya disease.Methods The clinical data of the adults with MMD were collected from January 2013 to January 2016 at the authors' hospital.All patients were followed up by the clinic reexamination,telephones or hospitalization.And then we evaluate the outcome of treatment of the surgery with the patients' modified Rankin Scale score and cerebral CT perfusion findings.The clinical data were analyzed by SPSS 20.0.Results 71 eligible patients were identified.The mean duration of follow-up is (27.3±8.6) months (7 to 36months).No patients were lost for follow-up.65 (85.9%) patients' clinical symptoms had been improved.There were significant differences in the result of mRS score and cerebral CT perfusion between the preoperative and the postoperative with statistical meanings (P< 0.05).Observing the end of the follow-up,there were postoperative complications in 9 cases,and cerebrovascular events in 11 cases.Conclusion STA-MCA anastomosis can increase cerebral blood supplying and improve clinical symptoms on the adult patients with Moyamoya disease,and it is an effective treatment for Moyamoya disease. |
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