| 马倩倩,于世鹏.CD4+T淋巴细胞与桥本氏甲状腺炎[J].济宁医学院学报,2015,(6):434-437,440 |
| CD4+T淋巴细胞与桥本氏甲状腺炎 |
| Research progress of CD4+ T lymphocytes in pathogenesis of hashimoto's thyroiditis |
| 投稿时间：2015-11-11 |
| DOI：10.3969/j.issn.1000-9760.2015.06.015 |
| 中文关键词: 桥本氏甲状腺炎|发病机制|CD4+T淋巴细胞 |
| 英文关键词: Hashimoto’s thyroiditis|Pathogenesis|CD4+T lymphocytes |
| 基金项目: |
| 作者 | 单位 | E-mail | | 马倩倩 | 济宁医学院2013级研究生, 山东济宁 272067
济宁医学院附属医院, 济宁 272029 | | | 于世鹏 | 济宁医学院2013级研究生, 山东济宁 272067
济宁医学院附属医院, 济宁 272029 | yushipengjn@163.com |
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| 中文摘要: |
| 桥本氏甲状腺炎(hashimoto's thyroiditis,HT)是引起甲状腺功能减退最常见的甲状腺疾病,在HT患者中有10%~15%可发生亚临床甲减,有0.1%~2%可发生临床甲减[1]。至今为止,HT的发病机制尚未完全阐明,其作为一种自身免疫性甲状腺疾病,CD4+T淋巴细胞及其细胞因子在该病的发生发展中扮演着重要的角色,本文就其与HT关系的研究进展作一综述。 |
| 英文摘要: |
| Hashimoto's thyroiditis (HT) is the most common cause of hypothyroidism in thyroid disease.It is reported that there are 10%~15% of HT will result in subclinical hypothyroidism,and 0.1%~2% will result in hypothyroidism.So far,the pathogenesis of HT is not fully understood.As an autoimmune thyroid disease,CD4+ T lymphocytes and their cytokines play an important role in the development of the disease.This review provides a summary of the relationship between CD4+ T lymphocytes and their cytokines with Hashimoto's thyroiditis. |
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