| 林祥晓,张成.血清CXCL10水平与特发性肺动脉高压预后的关系[J].济宁医学院学报,2014,(4):263-264,267 |
| 血清CXCL10水平与特发性肺动脉高压预后的关系 |
| Relationship between serunl CXCL10 levels and prognosis in idiopathic pulmonary arterial hypertension |
| 投稿时间：2014-07-01 |
| DOI：10.3969/j.issn.1000-9760.2014.04.009 |
| 中文关键词: 肺动脉高压;预后;趋化因子 |
| 英文关键词: Pulmonary hypertension;Prognosis;Chemokines |
| 基金项目:济宁医学院青年基金资助项目(编号:济医院字2009) |
| 作者 | 单位 | | 林祥晓 | 济宁医学院附属医院, 山东济宁 272029 | | 张成 | 济宁医学院附属医院, 山东济宁 272029 |
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| 中文摘要: |
| 目的 探讨血清CXCL10水平与特发性肺动脉高压(IPAH)预后的关系。方法 选择2009年1月至2012年12月间我院收治的IPAH患者40例,并对其进行随访,随访终点为全因死亡,对随访结果进行生存分析。结果 IPAH患者血清CXCL10水平明显高于正常人,生存曲线分析表明,血清CXCLl0≥225.5pg/ml的患者有较高的生存率。结论 血清CXCL10水平与IPAH患者的预后有密切关系,血清CXCL10水平越高,预后越好。 |
| 英文摘要: |
| Objective To explore the relationship between serum CXCL10 levels and prognosis in idiopathic pulmonary arterial hypertension(IPAH).Methods A total of 40 IPAH patients were enrolled consecutively and followed up until the endpoint of all-cause death.The results of the follow-up were carried on survival analysis.Results The serm level of CXCLl0 in IPAH was significantly higher than normal,and the higher level CXCLl0 group(the serum CXCLl0 ≧ 225.5 pg/ml) had a higher survival rate.Conclusion The serm level of CXCL10 correlates significantly with prognosis in IPAH.And a higher serm level of CXCL10 prediels better conditions and prognosis. |
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