| 谷昊明,郭立燕,刁玉涛.某校大学生乙型肝炎血清学标志物检测结果分析[J].济宁医学院学报,2013,(6):431-434 |
| 某校大学生乙型肝炎血清学标志物检测结果分析 |
| Analysis of hepatitis B virus serological markers among college students |
| 投稿时间：2013-09-13 |
| DOI：10.3969/j.issn.1000-9760.2013.06.020 |
| 中文关键词: 乙型肝炎;血清学检测 |
| 英文关键词: Hepatitis B Virus;Serological test |
| 基金项目: |
| 作者 | 单位 | E-mail | | 谷昊明 | 济南大学山东省医学科学院基础医学研究所, 山东济南 250062
济南大学山东省医学科学院医学与生命科学学院, 山东济南 250200
济宁医学院公共卫生学院, 山东济宁 272067 | | | 郭立燕 | 济宁医学院公共卫生学院, 山东济宁 272067 | | | 刁玉涛 | 济南大学山东省医学科学院基础医学研究所, 山东济南 250062 | dyutium@sina.com |
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| 中文摘要: |
| 目的 了解目前大学生乙型肝炎的感染情况,探讨在大学生中乙肝病毒血清标志物的表现模式及其构成比,不同模式的传染性及流行病学意义。方法 采用分层抽样法抽取某校227名在校大学生,用酶联免疫试验方法(ELISA)检测血清乙肝病毒表面抗原(HBsAg)、乙肝表面抗体(抗-HBs),乙肝病毒e抗原(HBeAg),乙肝病毒e抗体(抗-HBe),乙肝病毒核心抗体(抗-HBc),同时配以相应的问卷调查,收集相关的信息。用卡方检验分析乙肝总阳性率与各因素的关系。结果 227份血清标本检共出HBV血清标志物171份,总阳性率为75.3%。其中HBsAg阳性率为3.1%,抗-HBs阳性率为72.2%,HBeAg阳性率为1.3%,抗-HBe阳性率为5.3%,抗-HBc阳性率为11.0%,同时组成9种血清学模式。分析发现与乙肝总阳性率有关的因素有:是否接种过乙肝疫苗(χ2=16.646,P<0.05),来自农村还是城市(χ2=4.239,P<0.05)。结论 调查的大学生HBsAg携带率低于全国平均水平,抗-HBs阳性率高于全国平均水平,乙肝疫苗的接种有效地降低了乙肝感染率。 |
| 英文摘要: |
| Objective To understand the infectious status of hepatitis B virus among college students and determine the representation pattern and its constitution ratio of hepatitis B serology symbols in college students.as well as infectivity and epidemiological significance of different pattern.Methods 227 students of medical college were recruited.ELISA test kits were used to test the HBsAg,anti-HBs,HBeAg,anti-HBe,and anti-HBc.Relevant information was collected at the same time using a questionnaire.Results We found out 171 HBV serological symbols out of blood serum samples.The total positive rate was 75.3 percent.And the positive rate of HBsAg was 3.1% (7/227); the positive rate of anti-HBs was 72.2% (164/227); the positive rate of HBeAg was 1.3% (3/227); the positive rate of anti-HBe was 5.3% (12/227); the positive rate of anti-HBc was 11.0% (25/227).At the same time 9 kinds of serological patterns were composed.There were 2 significant factors which influence the total positive rate of Hepatitis B: Does the hepatitis B vaccine inoculation (χ2=16.646,P=0.000 <0.05) come from rural or urban (χ2=4.239,P=0.039 <0.05).Conclusion As for the students detected,the positive rate of HBsAg was lower and the positive rate of anti-HBs was higher than the national average.The vaccination of hepatitis B vaccine was effective in reducing hepatitis B infection. |
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