| 巩光平,孙晓斐,丛培玲,徐勤成,魏子秀.缬沙坦对房颤射频消融术后左房容积结构与功能的影响[J].济宁医学院学报,2013,(1):41-42,52 |
| 缬沙坦对房颤射频消融术后左房容积结构与功能的影响 |
| The effect of valsartan on left atrium volume after atrial fibrillation undergone radiofrequency ablation |
| 投稿时间：2012-12-03 |
| DOI：10.3969/j.issn.1000-9760.2013.01.012 |
| 中文关键词: 射频消融;房颤;左房内径;缬沙坦 |
| 英文关键词: Atrial fibrillation;Radiofrequency ablation;Left atrial diameter;Valsartan |
| 基金项目: |
| 作者 | 单位 | | 巩光平 | 济南大学山东省医学科学院医学与生命科学学院, 山东济南 250062
济宁医学院附属济宁市第一人民医院, 山东济宁 272011 | | 孙晓斐 | 济宁医学院附属济宁市第一人民医院, 山东济宁 272011 | | 丛培玲 | 济宁医学院附属济宁市第一人民医院, 山东济宁 272011 | | 徐勤成 | 济宁医学院附属济宁市第一人民医院, 山东济宁 272011 | | 魏子秀 | 济宁医学院附属济宁市第一人民医院, 山东济宁 272011 |
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| 中文摘要: |
| 目的 探讨血管紧张素原(AGT)对2型糖尿病肾病(DN)的影响。方法 将46例DN患者分为早期糖尿病肾病组(EDN组)20例、临床糖尿病肾病组(CDN组)26例,另有32例为正常对照组(NC组),采用ELISA法检测各组血清和尿中的AGT水平。结果 1)EDN组、CDN组较NC组血清AGT水平明显升高,有显著性差异(F值:54.327,P<0.05),而EDN组、CDN组之间无显著性差异;与EDN组比较,CDN组尿AGT水平高,NC组低,各组间有显著性差异(F值:207.113,P<0.05)。2)2型糖尿病肾病患者的血清AGT水平与尿AGT水平无相关性。结论 尿血管紧张素原可能是反映2型糖尿病肾病肾功能损害程度的指标。 |
| 英文摘要: |
| Objective To evaluate the effect of valsartan on the recurrence of atrial fibrillation,as well as left atrial diameter in patients with atrial fibrillation undergone radiofrequency ablation.Methods 40 patients were selected with atrial fibrillation received radiofrequency ablation.Patients were randomly divided into two group,namely valsartan group and control group,with 20 patients in each group.All patients with other dieseases took the original drug.Patients in valsartan group received valsartan 80mg one time a day.Control group take only the original drug.It was measured 1 weeks before operation,the postoperative 1 months,3 months,6 months,9 months left atrial diameter change.At the same time,it was observed Holter,atrial fibrillation recurrence change.Results After atrial fibrillation radiofrequency ablation,left atrial diameter was significantly reduced in two groups.After 1 months,3 months,6 months between the two groups it had no significant difference (P>0.05),but 9 months after operation,there were significant differences (P<0.05)in two groups.In the pairwise comparison,the recurrence rate of atrial fibrillation was no significant difference (P>0.05),which tended to be significant trends.Conclusion Left atrial diameter was significantly reduced in patients which took valsartan.Radiofrequency ablation of atrial fibrillation after taking valsartan had reduced the recurrence rate,but the difference was not significant.Key words:Atrial fibrillation;Radiofrequency ablation;Left atrial diameter;Valsartan |
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