文章摘要
聂尚丹,陈廷,赵建磊,刘婷.结核病患者单纯疱疹病毒感染的检测及临床意义[J].济宁医学院学报,2011,(6):413-415
结核病患者单纯疱疹病毒感染的检测及临床意义
The detection of tuberculosis patients with herpes simplex virus infection and clinical significance
投稿时间:2011-05-15  
DOI:10.3969/j.issn.1000-9760.2011.06.010
中文关键词: 结核病|单纯疱疹病毒|感染
英文关键词: Tuberculosis|Herpes simplex virus|Infection
基金项目:
作者单位
聂尚丹 济宁医学院医学检验系, 山东济宁 272067 
陈廷 济宁医学院继续教育学院, 山东济宁 272067 
赵建磊 胶州市第三人民医院, 山东胶州 266300 
刘婷 济宁医学院医学检验系2005级学生, 山东济宁 272067 
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中文摘要:
      目的 了解结核病患者单纯疱疹病毒的感染情况,探讨其可能对结核病病情的影响。方法 采用金标免疫斑点渗滤法分别检测51例肺结核患者和30例正常健康人血浆单纯疱疹病毒感染的IgM和IgG。结果 肺结核患者组HSV-IgM的阳性率为88.24%与对照组(66.67%)相比,差异有统计学意义(P<0.05);HSV-IgG的阳性率为80.39%,与对照组(70.00%)相比,差异无统计学意义(P>0.05);有肺炎表现者HSV-IgG的阳性率为61.11%,与无肺炎表现的患者组(90.91%)相比,差异有统计学意义(P<0.05);经统计学处理,HSV的活动性感染与病程、分期、痰涂片阳性无相关性(P>0.05)。结论 肺结核患者存在较高的活动性单纯疱疹病毒感染,活动性单纯疱疹病毒感染与病情轻重有一定关系。
英文摘要:
      Objective To learn about tuberculosis patients with herpes simplex virus infection and explore the possible impact of TB disease. Methods To test IgG and IgM of 51 cases of patients with tuberculosis as well as 30 cases of normal plasma with herpes simplex virus infection respectively by using gold immune spots filtration method. Results The HSV-IgM positive rate of the group of patients with tuberculosis was 88.24﹪compared with that of the matched group(66.67﹪), and the difference was statistically significant(P<0.05).However, the HSV-IgG positive rate was 80.39﹪ compared with that of the matched group(70.00﹪), and the difference was statistically significant(P>0.05).The HSV-IgG positive rate of the patients with pneumonia performance was 61.11﹪compared with that of patients without pneumonia performance(90.91﹪) and the difference was statistically significant(P<0.05).Through statistical processing it was affirmed that there was no relevance between the active infection of HSV and the course of disease, the stage, the positive of sputum smear(P>0.05). Conclusion The tuberculosis patients are more likely infected with active herpes simplex virus.There is some connection between active herpes simplex virus infection and the condition of illness.
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