| 赵丽,赵萌,王爱敏.带状疱疹后神经痛的危险因素[J].济宁医学院学报,2023,46(2):96-100 |
| 带状疱疹后神经痛的危险因素 |
| The risk factors of postherpetic neuralgia |
| 投稿时间：2022-12-31 |
| DOI：10.3969/j.issn.1000-9760.2023.02.005 |
| 中文关键词: 带状疱疹;带状疱疹后神经痛;危险因素 |
| 英文关键词: Herpes zoster;Postherpetic neuralgia;Risk factors |
| 基金项目: |
| 作者 | 单位 | E-mail | | 赵丽 | 济宁市第一人民医院, 济宁 272011
青岛大学医学部护理学院, 青岛 266003 | | | 赵萌 | 青岛大学医学部护理学院, 青岛 266003 | | | 王爱敏 | 青岛大学医学部护理学院, 青岛 266003 | mdr613@163.com |
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| 中文摘要: |
| 目的 探析带状疱疹后神经痛（postherpetic neuralgia，PHN）发生的危险因素。方法 收集2019年9月至2022年6月在济宁市第一人民医院皮肤科住院的800例带状疱疹患者临床资料，通过门诊随诊和电话随访，了解患者PHN发生情况，通过单因素及多因素二元logistic回归分析患者发生PHN的危险因素。结果 800例带状疱疹患者中，共有272例发生PHN （34%），多因素二元logistic回归分析显示年龄≥50岁（50岁～，OR=4.91，95%CI：2.3～10.48；60岁～，OR=6.98，95%CI：3.34～14.62；70岁～，OR=9.75，95%CI：4.45～21.34；80岁～，OR=4.19，95%CI：1.59～11.02）、冠状动脉粥样硬化性心脏病（OR=1.70，95%CI：1.04～2.78）、皮损程度为重度（OR=2.92，95%CI：1.2～7.13）、住院期间重度疼痛（OR=3.42，95%CI：1.49～7.82）是PHN发生的影响因素。结论 年龄≥50岁，有冠状动脉粥样硬化性心脏病史、住院期间重度疼痛、重度皮损是PHN发生的危险因素。 |
| 英文摘要: |
| Objective To investigate the risk factors of postherpetic neuralgia (PHN).Methods The clinical data of 800 patients with herpes zoster hospitalized in the dermatology department of Jining No 1 People's Hospital from September 2019 to June 2022 were collected.PHN was detected by outpatient and telephone follow-up.Univariate and multivariate binary logistic regression were used to analyze the risk factors of PHN.Results Among 800 patients with herpes zoster, 272 patients (34%) developed PHN.Univariate and multivariate binary logistic regression analysis showed age ≥ 50 years (50 years old~, OR=4.91, 95%CI:2.3~10.48;60 years old~, OR=6.98, 95%CI:3.34~14.62;70 years old~, OR=9.75, 95%CI:4.45~21.34;80 years old~, OR=4.19, 95%CI:1.59~11.02), complicated with coronary atherosclerotic heart disease (OR=1.70, 95%CI:1.04~2.78), severe skin lesions (OR=2.92, 95%CI:1.2~7.13), and severe pain during hospitalization (OR=3.42, 95%CI:1.49~7.82) were the influence factors of PHN.Conclusions Age ≥ 50 years, a history of coronary atherosclerotic heart disease, severe pain during hospitalization, and severe skin lesions are risk factors for PHN. |
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