| 郝建华,张传芝,刘明,周亚楠,陈敏.精神分裂症患者认知功能与社会功能的关系[J].济宁医学院学报,2023,46(1):20-25 |
| 精神分裂症患者认知功能与社会功能的关系 |
| The relationship between cognitive function and social function in patients with schizophrenia |
| 投稿时间：2022-03-09 |
| DOI：10.3969/j.issn.1000-9760.2023.01.005 |
| 中文关键词: 精神分裂症;认知功能;社会功能;信息处理速度 |
| 英文关键词: Schizophrenia;Cognitive function;Social function;Speed of processing |
| 基金项目:济宁医学院教师科研扶持基金重点项目(JY2017JS007);山东省医药卫生科技发展计划项目(202003090370) |
| 作者 | 单位 | E-mail | | 郝建华 | 济宁医学院精神卫生学院, 济宁 272013
苏州大学教育学院, 苏州 215000 | | | 张传芝 | 济宁医学院附属第二医院, 济宁 272051 | | | 刘明 | 菏泽市精神卫生中心, 菏泽 274006 | | | 周亚楠 | 济宁医学院附属第二医院, 济宁 272051 | | | 陈敏 | 济宁医学院精神卫生学院, 济宁 272013 | cm7697@163.com |
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| 中文摘要: |
| 目的 探讨精神分裂症患者的认知功能和社会功能状况及其关系。方法 采用中文版精神分裂症认知功能成套测验(Matrics Consensus Cognitive Battery,MCCB)和个人和社会功能量表(Personal and Social Performance Scale,PSP)对100名精神分裂症患者和101名正常个体的认知功能(信息处理速度、言语记忆和工作记忆)和社会功能实施测试,比较两组的测验结果,并对认知功能与社会功能的关系进行相关分析及回归分析。结果 1)精神分裂症组认知功能测验分数和社会功能分数均显著低于健康对照组(P<0.001)。2)男性精神分裂症患者的社会功能分数比女性患者更高(t=3.473,P=0.001);受教育年限＞9年的精神分裂症患者的各认知功能和社会功能分数均显著高于受教育年限低于≤9年的患者(P<0.05);年龄＞41岁的精神分裂症患者的各认知功能分数均显著低于≤41岁患者的(P<0.05);病程＞16年的精神分裂症患者在信息处理速度方面显著差于病程≤16年的患者(P<0.05),并且在言语学习方面显著差于病程在6~15年的患者(P<0.05)。3)精神分裂症患者PSP总分与信息处理速度(r=0.348,P<0.05)、言语记忆(r=0.220,P<0.05)、工作记忆(r=0.308,P<0.05)呈正相关;逐步回归分析显示,信息处理速度可以有效预测社会功能(B=0.729,P<0.05)。结论 精神分裂症患者存在认知功能损害和社会功能损害,其认知功能受到了受教育年限、年龄、病程的影响,社会功能受到了性别、受教育年限的影响。精神分裂症患者的信息处理速度可以预测社会功能状况。 |
| 英文摘要: |
| Objective To investigate the cognitive and social functions and their relationship in patients with schizophrenia.Methods The Matrics Consensus Cognitive Battery(MCCB) and the Personal and Social Performance Scale (PSP) were used to test the cognitive function (the speed of processing,verbal memory and working memory) and social function in 100 schizophrenic patients and 101 normal subjects.The results of the two groups were compared,and the relationship between cognitive function and social function was analyzed by correlation analysis and regression analysis.Results 1) The schizophrenia group had significantly lower scores on all cognitive function tests and social function scores than the healthy control group (P<0.001).2) Male patients with schizophrenia had higher social functioning scores than female patients (t=3.473,P=0.001).Patients with schizophrenia with more than 9 years of education had significantly higher scores for each cognitive and social function than patients with less than 9 years of education (P<0.05).In terms of Speed of processing,verbal memory and working memory,schizophrenics older than 40 years of age were worse than those younger than 41 years of age(P<0.05).The speed of processing patients with schizophrenia with disease course of more than 16 years was significantly worse than that of patients with disease course of less than 16 years (P<0.05),and the speech learning was significantly worse than that of patients with disease course of more than 6~15 years (P<0.05).3) The total score of PSP was significantly positively correlated with speed of processing(r=0.348,P<0.05),verbal memory(r=0.220,P<0.05) and working memory (r=0.308,P<0.05).The stepwise regression analysis showed that speed of processing could effectively predict social function(B=0.729,P<0.05).Conclusion Schizophrenia patients have cognitive impairment and social impairment,and their cognitive function is influenced by age and course of disease,social functioning is influenced by gender,years of schooling.Speed of processing can predict social functioning in patients with schizophrenia. |
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