文章摘要
袁梓健,郭立燕,张妍,刘苗苗.中国老年人轻度认知障碍现状及其影响因素[J].济宁医学院学报,2022,45(3):183-188
中国老年人轻度认知障碍现状及其影响因素
A systematic review of the prevalence and influencing factors of mild cognitive impairment in Chinese elderly population
投稿时间:2022-04-30  
DOI:10.3969/j.issn.1000-9760.2022.03.007
中文关键词: 轻度认知障碍;认知功能障碍;患病率;系统综述
英文关键词: Mild cognitive impairment;Cognitive impairment;Prevalence;Systematic review
基金项目:山东省高等学校科技计划项目(J18KA298)
作者单位E-mail
袁梓健 济宁医学院公共卫生学院, 济宁 272013  
郭立燕 济宁医学院公共卫生学院, 济宁 272013  
张妍 济宁医学院公共卫生学院, 济宁 272013  
刘苗苗 济宁医学院公共卫生学院, 济宁 272013 miao1206@126.com 
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中文摘要:
      目的 系统检索有关中国老年人轻度认知障碍(MCI)的文献,探讨中国老年人群认知障碍现状及其影响因素。方法 2022年1-3月系统检索中国知网、万方、维普、Pub Med、Web of Science和Google Scholar数据库中发表的有关中国老年人MCI患病率的文献。根据纳入及排除标准筛选文献,然后进行质量评价,提取文献中患病率及其他相关数据,利用Stata12.0软件合并患病率,按照不同人群特征进行亚组分析。通过排除低质量文献进行敏感性分析,通过Egger检验和绘制漏斗图评估发表偏倚。结果 本研究共纳入32篇文献,样本量共计103521例,其中检出MCI患者21190例。中国老年人群 MCI患病率约为 20.8%(95%CI:18.3%~23.2%)。女性MCI患病率为22.2%(95%CI:19.1%~25.2%)高于男性18.8%(95%CI:16.5%~21.0%),差异有统计学意义(P<0.05)。随着年龄的增加,MCI的患病率逐渐增高。文盲组MCI患病率为30.8%(95%CI:25.9%~35.7%),非文盲组MCI患病率为17.0%(95%CI:13.8%~20.3%),差异有统计学意义(P<0.05)。城市MCI患病率为16.6%(95%CI:12.6%~20.6%)低于农村22.2%(95%CI:12.8%~31.5%),差异有统计学意义(P<0.05)。从地理位置来看,北方地区老年人MCI患病率为21.5%(95%CI:15.9%~27.1%),南方地区老年人MCI患病率为20.6%(95%CI:17.1%~24.0%),差异有统计学意义(P<0.05)。结论 近10年来,中国老年人 MCI 患病率逐渐上升,已成为我国重要的公共卫生问题。性别、年龄、文化水平、城乡及地域是影响老年 MCI 患病率的主要因素。
英文摘要:
      Objective To investigate the prevalence and influencing factors of mild cognitive impairment (MCI) in Chinese elderly population through systematic review.Methods From January to March,2022,the literature search on the prevalence of mild cognitive impairment in the elderly Chinese published in CNKI,Wan fang,CQVIP,Pub Med,Web of Science and Google Scholar databases was conducted.After selecting the literature according to the inclusion and exclusion criteria,the quality of the literature was evaluated according to the Agency for Healthcare Research and Quality (AHRQ).The prevalence rate and other relevant data in the literature were extracted.Subgroup analysis was performed according to population characteristics by using Stata 12.0 software.Sensitivity analysis was carried out by excluding low-quality literature,and the publication bias was evaluated by Egger's test and funnel plot.Results A total of 32 literature were included in this study,with a sample of 103521 people.The results showed that the overall prevalence of MCI in Chinese elderly population was 20.8% (95%CI:18.3%~23.2%),with 21190 MCI patients.The prevalence of MCI in female was 22.2% (95%CI:19.1%~25.2%),which was higher than 18.8% (95%CI:16.5%~21.0%) in male (P<0.05).The prevalence of MCI increases with the increase of age.The prevalence of MCI in illiterate group was 30.8% (95%CI:25.9%~35.7%),and that in non-illiterate group was 17.0% (95%CI:13.8%~20.3%),and the difference was statistically significant (P<0.05).The prevalence of MCI in urban areas was 16.6% (95%CI:12.6%~20.6%),which was lower than that in rural areas 22.2% (95%CI:12.8%~31.5%).The difference was statistically significant (P<0.05).Geographically,the prevalence of MCI in northern China was 21.5% (95%CI:15.9%~27.1%),which was higher than that of the Southern China(20.6%,95%CI:17.1%~24.0%).Conclusion In the last decade,the prevalence of MCI among the elderly in China is about 20.8%,which has become an important public health problem.Gender,age,education level,urban and rural areas and region are the main factors affecting the prevalence of MCI in the elderly.
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