| .脂质代谢与阿尔茨海默病[J].济宁医学院学报,2022,45(2):135-139 |
| 脂质代谢与阿尔茨海默病 |
| Research progress on lipid metabolism and pathogenesis of Alzheimer's disease |
| 投稿时间：2021-05-27 |
| DOI：10.3969/j.issn.1000-9760.2022.02.015 |
| 中文关键词: 脂类代谢;阿尔茨海默病;生物标志物;发病机制 |
| 英文关键词: Lipid metabolism;Alzheimer's disease;Biomarkers;Pathogenesis |
| 基金项目:济宁医学院大学生创新训练计划(cx2019091) |
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| 1.济宁医学院临床医学院，济宁 272013;2.济宁医学院精神卫生学院，济宁 272013 |
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| 中文摘要: |
| 脂质作为细胞膜的基本成分，对人体健康和大脑功能起着重要作用，与阿尔茨海默病(Alzheimer's disease, AD)的发病机制密切有关。深入了解脂质与AD的关系对阐释该病的发病机制至关重要，有助于发现该病的干预和治疗的生物标志物。本文系统总结脂类代谢与AD发病机制的研究进展，为该病的病因机制研究提供科学依据。 |
| 英文摘要: |
| Lipid, as the basic component of cell membrane, plays an important role in human health and brain function.It is closely related to the pathogenesis of Alzheimer's disease.It is very important to understand the relationship between lipid and Alzheimer's disease, and to find biomarkers for intervention and treatment.This article will systematically summarize the research progress of lipid metabolism and the pathogenesis of Alzheimer's disease, and provide scientific basis for the study of the etiological mechanism of Alzheimer's disease. |
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