| 吕锋,李建军.特发性肉芽肿性乳腺炎的诊断及治疗现状[J].济宁医学院学报,2020,43(2):132-136 |
| 特发性肉芽肿性乳腺炎的诊断及治疗现状 |
| Diagnosis challenge and treatment status of idiopathic granulomatous mastitis |
| 投稿时间：2019-12-17 |
| DOI：10.3969/j.issn.1000-9760.2020.02.014 |
| 中文关键词: 特发性肉芽肿性乳腺炎;诊断;治疗现状 |
| 英文关键词: Idiopathic granulomatous mastitis;Treatment status;Diagnostic challenges |
| 基金项目:山东省医药卫生科技发展计划项目（2016WS0162） |
| 作者 | 单位 | E-mail | | 吕锋 | 济宁医学院临床医学院, 济宁 272013
济宁医学院, 济宁 272067 | | | 李建军 | 济宁医学院临床医学院, 济宁 272013
济宁医学院, 济宁 272067 | lixu16@sohu.com |
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| 中文摘要: |
| 特发性肉芽肿性乳腺炎(idiopathic granulomatous mastitis,IGM)是一种罕见的良性慢性炎症性乳腺疾病,好发于有母乳喂养史的育龄期妇女。创伤、激素紊乱、自身免疫反应和Kro-ppenstedtii棒状杆菌感染等均与该疾病发生相关,而确切病因尚未清楚。IGM在影像学和临床表现上与乳腺癌极其相似,通常以乳腺局部肿块伴疼痛、脓肿、瘘等症状出现;乳腺超声、钼靶摄片及磁共振等影像学检查不具有特异性,最终确诊依赖组织病理学,以乳腺小叶为中心的非干酪样坏死性肉芽肿为特征。目前IGM的治疗包括手术切除、药物治疗、密切观察、中医中药治疗等方法,但无最佳治疗方案。本文就IGM的病因、发病机制、临床表现、诊断以及治疗现状做一综述。 |
| 英文摘要: |
| Idiopathic granulomatous mastitis(IGM)is a rare benign chronic inflammatory breast disease,which occurs in women of childbearing age with a history of breastfeeding.Inflammation as the result of a reaction to trauma,metabolic or hormonal processes,autoimmunity,and an infection with Corynebacterium Kroppenstedtii have all been implicated.IGM is very similar to breast cancer in imaging and clinical manifestations usually with local breast masses accompanied by pain,abscess,fistula and other symptoms.Breast ultrasound,mammography and MRI are not specific,and the final diagnosis depends on histopathology characterized by non caseous necrotic granuloma centered on breast lobules.At present,the treatment of IGM includes surgical resection,drug treatment,close observation and traditional Chinese medicine treatment,but there is no optimal treatment.This article reviews the etiology,clinical manifestations,diagnosis and treatment of IGM. |
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