周新明,刘翠.原发性胃癌根治术后再发残胃癌危险因素临床观察[J].济宁医学院学报,2016,39(4):248-250,257 |
原发性胃癌根治术后再发残胃癌危险因素临床观察 |
An observation of the risks of remnant gastric cancer after the radical resection of primary gastric cancer |
投稿时间:2016-03-02 |
DOI:10.3969/j.issn.1000-9760.2016.04.006 |
中文关键词: 原发性胃癌;残胃癌;Bormann分型;TNM分期;危险因素 |
英文关键词: Primary gastric cancer;Remnant gastric cancer;Bormann classification;Clinical stage;Risk factors |
基金项目: |
作者 | 单位 | 周新明 | 滕州市中心人民医院, 滕州 277500 | 刘翠 | 滕州市中心人民医院, 滕州 277500 |
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中文摘要: |
目的 探讨原发性胃癌行胃癌根治术后发生残胃癌的相关危险因素。方法 我院2004年7月至2014年7月收治并行胃癌根治术的原发性胃癌患者203例,69例在根治术后发生残胃癌,为观察组;134例未发生残胃癌的患者为对照组。对比两组的一般临床资料、Bormann分型、TNM分期、手术方式和残胃状况进行单因素和多因素回归分析。结果 1)原发性胃癌BormannⅠ、Ⅱ型和TNM分期Ⅰ、Ⅱ期中观察组所占比例少于对照组,而Ⅲ、Ⅳ型和Ⅲ、Ⅳ期则多于对照组;2)观察组胆汁反流、Hp感染、低胃酸和残胃炎明显多于对照组;3)logistic回归分析显示残胃癌与年龄、吸烟、Hp感染、低胃酸、手术方式、TNM分期因素有关(P<0.05),与性别、血型和饮酒无关(P>0.05)。结论 原发性胃癌的Bormann分型、TNM分期、年龄、吸烟、Hp感染、低胃酸、手术方式均是残胃癌发生的危险因素。 |
英文摘要: |
Objective Objective:Observe the relative risks of remnant gastric cancer after radical surgery. Methods Collected 203 cases of gastric cancer after radical resection in our hospital from July 2004 to July 2014,including 69 cases of remnant gastric cancer (remnant group),the other 134 cases without the occurrence of remnant gastric cancer (control group).Compared the general clinical data,Bormann classification,clinical stage,histological type,operation mode and the remnant stomach status of the two groups.Then analyzed the data with univariate and multivariate regression analysis. Results 1)Bormann type I,II and clinical stage I,II of the primary gastric cancer in the remnant group were less than that in control group,and the papillary adenocarcinoma in the remnant group were less than that in the control group,but Bormann type III,IV and clinical stage III,IV in the remnant group were more than that in control group;2) There were more patients with bile reflux,Hp infection,low acid and local inflammation in the remnant group than that in control group;3) Logistic multivariate regression analysis showed that the occurrence of remnant gastric cancer were closely related with age,smoking,Hp infection,low gastric acid,operation mode,clinical stage and histological types (P<0.05),and had no significant correlation with sexuality,blood types and alcohol consumption (P>0.05)。Conclusion Bormann classification,clinical stage and histological type of primary gastric cancer,age,smoking,Hp infection,low gastric acid,operations are risk factors for remnant gastric cancer. |
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