李锦,孔令斌,黄志诚.结直肠腺瘤性息肉癌变机制研究进展[J].济宁医学院学报,2016,39(3):196-201 |
结直肠腺瘤性息肉癌变机制研究进展 |
Advances in the mechanism of the colorectal adenomatous polyps carcinogenesis |
投稿时间:2015-07-17 |
DOI:10.3969/j.issn.1000-9760.2016.03.013 |
中文关键词: 结直肠腺瘤性息肉;癌变 |
英文关键词: Colorectal adenomatous polyps;Canceration |
基金项目:山东省医药卫生科技发展计划(2013WS0335) |
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中文摘要: |
腺瘤性息肉是结直肠中最常见的病变之一,研究报道腺瘤性息肉是结直肠癌的癌前病变,其中50%~ 70%的结直肠癌来源于腺瘤性息肉。腺瘤性息肉一旦发生癌变,治疗效果多不理想,因此,探讨结直肠腺瘤性息肉(colorectal adenomatous polyps,CAP)癌变的发生因素及其机制,有针对性的早期干预具有重要的意义。本文仅就CAP癌变发生的危险因素及其机制的研究进展综述如下。 |
英文摘要: |
Colorectal adenomatous polyposis is one of the most common diseases in colorectal.The study reported that the colorectal adenomatous polyps is the precancerous lesions of colorectal cancer,of which 50% to 70% of colorectal cancer comes from colorectal adenomatous polyps.Once colorectal adenomatous polyposis is canceration,treatment is often unsatisfactory.Therefore,the colorectal adenomatous polyps occurrence factors and mechanisms are to be explored.The early intervention is of great significance.In this paper,the research progress on the risk factors and mechanisms of carcinogenesis of colorectal adenoma polyps is summarized as following. |
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