张妍,翟敏,盛学文,梁余良.中国居民不同类型饮用水与食管癌发病的Meta分析[J].济宁医学院学报,2015,(3):200-204 |
中国居民不同类型饮用水与食管癌发病的Meta分析 |
Meta-analysis on the different types of drinking water and esophagus cancer in China |
投稿时间:2015-03-09 |
DOI:10.3969/j.issn.1000-9760.2015.03.015 |
中文关键词: 食管癌;饮水;Meta分析 |
英文关键词: Esophagesl cancer;Water factors;Meta-analysis |
基金项目:山东省医药卫生科技发展计划项目(编号:2011HZ 015) |
作者 | 单位 | 张妍 | 济宁医学院公共卫生学院, 山东济宁 272067 | 翟敏 | 济宁医学院公共卫生学院, 山东济宁 272067 | 盛学文 | 济宁医学院2008级预防医学本科生, 济宁 272067 | 梁余良 | 济宁医学院2008级预防医学本科生, 济宁 272067 |
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中文摘要: |
目的 摘要:目的 定量综合评价饮水因素在食管癌发病过程中的作用。方法 应用Meta分析方法对国内外有关不同类型饮用水与食管癌关系的研究进行定量综合分析,用固定效应模型或随机效应模型计算合并OR值及其95%CI。结果 饮用自来水、清洁水与食管癌无关联性,合并效应值为0.73(0.44,1.20);饮用未经处理水为食管癌的危险因素,合并效应值为1.73(1.27,2.37),其中饮用井水和沟塘水有统计学意义,合并效应值分别为1.48(1.23,1.79)和2.64(1.70,4.09),而饮用河水/湖水无统计学意义,合并效应值为1.09(0.56,2.10)。结论 居民饮用未经处理的不洁水或污染水为食管癌的致癌因子。 |
英文摘要: |
Objective To evaluate the role of the water factors in the incidence of esophagus cancer.Methods Meta-analysis was used to study the relationship of drinking water factors and esophageal cancer at home and abroad.Fixed effect model and random effect model were selected to calculate the pooled OR and its corresponding 95%.Results The association was not found in drinking tap water/clean water and esophageal cancer,and the ORc was 0.73(0.44,1.20).Untreated drinking water was a risk factor for esophageal cancer with the ORc 1.73(1.27,2.37),in which there was statistically significant differences of drinking ditch ponds and wells water with the ORc 2.64(1.70,4.09)and 1.48(1.23,1.79),while we did not found significant difference of drinking river and lake water with its ORc 1.09(0.56,2.10).Conclusion Untreated or contaminated water were esophageal carcinogens. |
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